The BuMPy Road to COPD Gene Discovery
نویسنده
چکیده
Article history: Received 5 February 2016 Accepted 5 February 2016 Available online 6 February 2016 BMPR2 variants and COPD in a southern Chinese population (Wang et al., 2016). They investigated two polymorphisms in the 3′ untranslated region of the BMPR2 gene. The 3′ untranslated region of an mRNA molecule is the sequence following the termination codon and plays an important role in the regulation of gene expression. Wang et al. found that the less frequent allele of both variants was associated with
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